Tools
GEPHI
The Open Graph Viz Platform Gephi is an interactive visualization and exploration platform for all kinds of networks and complex systems, dynamic and hierarchical graphs. Runs on Windows, Linux and Mac OS X. Gephi is open-source and free.
http://wiki.gephi.org/index.php/Gephi_Research
AnalyzeDirect
AnalyzeDirect offers several products associated with Mayo Clinic's Analyze software.
Analyze 10.0 is a powerful, comprehensive software package for multi-dimensional display, processing, segmentation, registration and measurement of multi-modality biomedical images.
InterSystems
InterSystems Caché® is an advanced object database that provides in-memory speed with persistence, and the ability to handle huge volumes of transactional data.